In Situ Observation of Spherical DNA Assembly “Nucleo-cages” in Water and Their Stabilization by Photocrosslinking

Formation of spherical microstructures from three-way junction DNA is observed in water by confocal laser scanning fluorescence microscopy (CLSM). Photocrosslinking of nucleo-cages by psoralen derivatives is shown to effectively increase their stability against heat and urea.

Saved in:
Bibliographic Details
Published in:Chemistry letters 2006-05, Vol.35 (5), p.486-487
Main Authors: Kim, Kwonil, Masumoto, Kouzou, Matsuura, Kazunori, Kimizuka, Nobuo
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Formation of spherical microstructures from three-way junction DNA is observed in water by confocal laser scanning fluorescence microscopy (CLSM). Photocrosslinking of nucleo-cages by psoralen derivatives is shown to effectively increase their stability against heat and urea.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2006.486