Comparison of femoral strength and fracture risk index derived from DXA-based finite element analysis for stratifying hip fracture risk: A cross-sectional study

Dual-energy X-ray absorptiometry (DXA)-based finite element analysis (FEA) has been studied for assessment of hip fracture risk. Femoral strength (FS) is the maximum force that the femur can sustain before its weakest region reaches the yielding limit. Fracture risk index (FRI), which also considers...

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Bibliographic Details
Published in:Bone (New York, N.Y.) N.Y.), 2018-05, Vol.110, p.386-391
Main Authors: Yang, Shuman, Luo, Yunhua, Yang, Lang, Dall'Ara, Enrico, Eastell, Richard, Goertzen, Andrew L., McCloskey, Eugene V., Leslie, William D., Lix, Lisa M.
Format: Article
Language:English
Subjects:
Absorptiometry, Photon - methods
Aged
Aged, 80 and over
Bone Density
Cross-Sectional Studies
Dual energy x-ray absorptiometry
Female
Femoral strength
Finite Element Analysis
Fracture risk
Hip fracture
Hip Fractures - diagnostic imaging
Humans
Logistic Models
Male
Osteoporosis
Osteoporosis - diagnostic imaging
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Summary:Dual-energy X-ray absorptiometry (DXA)-based finite element analysis (FEA) has been studied for assessment of hip fracture risk. Femoral strength (FS) is the maximum force that the femur can sustain before its weakest region reaches the yielding limit. Fracture risk index (FRI), which also considers subject-specific impact force, is defined as the ratio of von Mises stress induced by a sideways fall to the bone yield stress over the proximal femur. We compared risk stratification for prior hip fracture using FS and FRI derived from DXA-based FEA. The study cohort included women aged ≥65years undergoing baseline hip DXA, with femoral neck T-scores
ISSN:8756-3282
1873-2763
DOI:10.1016/j.bone.2018.03.005