Intravoxel incoherent motion (IVIM) at 3.0 T: evaluation of early renal function changes in type 2 diabetic patients

Purpose The purpose of this study was to evaluate the utility of intravoxel incoherent motion diffusion-weighted imaging (IVIM DWI) parameters in identifying early renal function changes in diabetics. Methods A total of 40 patients with type 2 diabetes mellitus and 20 healthy control subjects underw...

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Bibliographic Details
Published in:Abdominal imaging 2018-10, Vol.43 (10), p.2764-2773
Main Authors: Feng, You-Zhen, Chen, Xiao-Qiao, Yu, Juan, Liu, Xiao-Ling, Cheng, Zhong-Yuan, Ren, Wei-Wei, Feng, Lie, Cai, Xiang-Ran
Format: Article
Language:English
Subjects:
Adult
Aged
Change detection
Correlation
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - physiopathology
Diabetic nephropathy
Diffusion Magnetic Resonance Imaging - methods
Epidermal growth factor receptors
Feasibility Studies
Female
Gastroenterology
Hepatology
Humans
Identification methods
Image Interpretation, Computer-Assisted - methods
Imaging
Kidney - diagnostic imaging
Kidney - physiopathology
Male
Mathematical analysis
Medicine
Medicine & Public Health
Middle Aged
Neuroimaging
Parameter identification
Parameters
Patients
Proteinuria
Radiology
Renal cortex
Renal function
Sensitivity and Specificity
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Summary:Purpose The purpose of this study was to evaluate the utility of intravoxel incoherent motion diffusion-weighted imaging (IVIM DWI) parameters in identifying early renal function changes in diabetics. Methods A total of 40 patients with type 2 diabetes mellitus and 20 healthy control subjects underwent multiple b value DWI. The diabetic patients were stratified into two groups based on albuminuria category: NAU (normal to mildly increased albuminuria; ACR 
ISSN:2366-004X
2366-0058
DOI:10.1007/s00261-018-1555-7