Ovarian metastasis in patients with endometrial cancer: risk factors and impact on survival

Background Oophorectomy is generally performed in patients with endometrial cancer despite the rate of ovarian metastasis being relatively low. Patients and methods A multicenter retrospective registry-based study was performed in 2329 patients with endometrial cancer. The outcome measures were the...

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Bibliographic Details
Published in:Journal of cancer research and clinical oncology 2018-06, Vol.144 (6), p.1103-1107
Main Authors: Ignatov, Tanja, Eggemann, Holm, Burger, Elke, Ortmann, Olaf, Costa, Serban Dan, Ignatov, Atanas
Format: Article
Language:English
Subjects:
Cancer
Cancer Research
Endometrial cancer
Endometrium
Health risk assessment
Hematology
Histology
Internal Medicine
Lymph
Medicine
Medicine & Public Health
Metastases
Metastasis
Myometrium
Oncology
Original Article – Clinical Oncology
Ovariectomy
Preservation
Risk factors
Survival
Tumors
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Summary:Background Oophorectomy is generally performed in patients with endometrial cancer despite the rate of ovarian metastasis being relatively low. Patients and methods A multicenter retrospective registry-based study was performed in 2329 patients with endometrial cancer. The outcome measures were the incidence of ovarian metastasis and the impact on overall survival. Results Median follow-up was performed at 84 months. A total of 2158 women were eligible for analysis, of which 131 (6.1%) had ovarian metastasis. Women with ovarian metastasis were more likely to have > 50% myometrial invasion, undifferentiated nonendometrioid tumors, and lymph and vascular space invasion. The presence of
ISSN:0171-5216
1432-1335
DOI:10.1007/s00432-018-2628-2