Distant supratentorial recurrence of craniopharyngioma

The patient's visual symptoms improved but he had persistent diabetes insipidus and hypothyroidism (thyroxine (T) 4: 3.5 nmg/dl; T3: 10 nmg/dl; thyroid-stimulating hormone: 0.2 mIU/dl; and, cortisol: 12 μg/dl) in the postoperative period. {Figure 5} Histopathological examination showed a cystic...

Full description

Saved in:
Bibliographic Details
Published in:Neurology India 2018-03, Vol.66 (2), p.564-566
Main Authors: Egoor, Ananth, Rajesh, Alugolu, Uppin, Megha, Saradhi, M
Format: Article
Language:English
Subjects:
Neurosurgery
NMR
Nuclear magnetic resonance
Thyroid gland
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The patient's visual symptoms improved but he had persistent diabetes insipidus and hypothyroidism (thyroxine (T) 4: 3.5 nmg/dl; T3: 10 nmg/dl; thyroid-stimulating hormone: 0.2 mIU/dl; and, cortisol: 12 μg/dl) in the postoperative period. {Figure 5} Histopathological examination showed a cystic lesion lined by stratified squamous epithelium and wet keratin, that on a higher magnification showed nests and trabeculae of cells with peripheral palisading and central stellate reticulum, which was characteristic of an adamantinomatous craniopharyngioma (the same histological type as the primary tumor) [Figure 6]. There are two defined mechanisms for the ectopic recurrences viz., seeding along the surgical route during the primary resection, the most common route of ectopic spread, or the spillage into the cerebrospinal fluid (CSF), which may allow viable tumor cells to migrate within the subarachnoid and even the intraventricular space.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.227330