Associations of maternal iodine status and thyroid function with adverse pregnancy outcomes in Henan Province of China

The study aimed to explore the effects of maternal iodine status and thyroid diseases on adverse pregnancy outcomes. A prospective study was conducted on 2347 pregnant women, who provided 2347 urinary samples tested for iodine, 1082 serum samples tested for thyroid function, and 2347 questionnaires...

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Bibliographic Details
Published in:Journal of trace elements in medicine and biology 2018-05, Vol.47, p.104-110
Main Authors: Yang, Jin, Liu, Yang, Liu, Hongjie, Zheng, Heming, Li, Xiaofeng, Zhu, Lin, Wang, Zhe
Format: Article
Language:English
Subjects:
Iodine
Maternal
Outcomes
Pregnancy
Thyroid dysfunction
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Summary:The study aimed to explore the effects of maternal iodine status and thyroid diseases on adverse pregnancy outcomes. A prospective study was conducted on 2347 pregnant women, who provided 2347 urinary samples tested for iodine, 1082 serum samples tested for thyroid function, and 2347 questionnaires about demographic information. Their pregnancy outcomes were recorded and compared between different urinary iodine concentration (UIC) and thyroid function groups. Pregnant women with UIC between 150 and 249 μg/L had lower incidences of preeclampsia (adjusted odds ratio (OR) 0.12, 95% CI: 0.01-0.87), placenta previa (adjusted OR 0.06, 95% CI: 0.01-0.69) and fetal distress (adjusted OR 0.10, 95% CI: 0.02-0.64) than the reference group (UIC 
ISSN:0946-672X
1878-3252
DOI:10.1016/j.jtemb.2018.01.013