Central Line–Associated Bloodstream Infection among Children with Intestinal Failure Presenting to the Emergency Department with Fever

To determine which factors confer the greatest risk of central line–associated bloodstream infection (CLABSI) in children with intestinal failure and fever presenting to an emergency department (ED), and to assess whether a low-risk group exists that may not require the standard treatment of admissi...

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Bibliographic Details
Published in:The Journal of pediatrics 2018-05, Vol.196, p.237-243.e1
Main Authors: Eisenberg, Matthew, Monuteaux, Michael C., Fell, Gillian, Goldberg, Vera, Puder, Mark, Hudgins, Joel
Format: Article
Language:English
Subjects:
central line–associated bloodstream infection
pediatric emergency medicine
short bowel syndrome
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Summary:To determine which factors confer the greatest risk of central line–associated bloodstream infection (CLABSI) in children with intestinal failure and fever presenting to an emergency department (ED), and to assess whether a low-risk group exists that may not require the standard treatment of admission for 48 hours on intravenous antibiotics pending culture results. This retrospective cohort study included children with intestinal failure and fever presenting to an ED over a 6-year period. Multivariable models were created using risk factors selected a priori to be associated with CLABSI as well as univariate predictors with P 
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2018.01.035