Interplay between regulation by methylation and noncoding RNAs in cancers

Cancer is one of the most important health problems today; therefore, many researchers are focusing on exploring the mechanisms underlying its development and treatment. The field of cancer epigenetics has flourished in recent decades, and studies have shown that different epigenetic events, such as...

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Bibliographic Details
Published in:European journal of cancer prevention 2018-07, Vol.27 (4), p.418-424
Main Authors: Lu, Chun-Xiao, Wu, Xiao-Li, Zhang, Guang-Yuan, Gu, Xiao-Ting, Ma, Xin, He, Dong-Xu
Format: Article
Language:English
Subjects:
Biomarkers, Tumor - genetics
DNA Methylation
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
Humans
Neoplasms - genetics
Neoplasms - pathology
RNA, Untranslated - genetics
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Summary:Cancer is one of the most important health problems today; therefore, many researchers are focusing on exploring the mechanisms underlying its development and treatment. The field of cancer epigenetics has flourished in recent decades, and studies have shown that different epigenetic events, such as DNA methylation, histone modification, and noncoding RNA regulation, work together to influence cancer development and progression. In this short review, we summarize the interactions between methylation and noncoding RNAs that affect cancer development.
ISSN:0959-8278
1473-5709
DOI:10.1097/CEJ.0000000000000433