Modelling Immune System: Principles, Models, Analysis and Perspectives

The biological immune system is a complex adaptive system. There are lots of benefits for building the model of the immune system. For biological researchers, they can test some hypotheses about the infection process or simulate the responses of some drugs. For computer researchers, they can build d...

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Bibliographic Details
Published in:Journal of bionics engineering 2009-03, Vol.6 (1), p.77-85
Main Authors: Li, Xiang-hua, Wang, Zheng-xuan, Lu, Tian-yang, Che, Xiang-jiu
Format: Article
Language:English
Subjects:
agent-based simulation
Artificial Intelligence
Biochemical Engineering
Bioinformatics
Biomaterials
Biomedical Engineering and Bioengineering
Biomedical Engineering/Biotechnology
complex adaptive system (CAS)
Engineering
HIV
immune system modelling
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Summary:The biological immune system is a complex adaptive system. There are lots of benefits for building the model of the immune system. For biological researchers, they can test some hypotheses about the infection process or simulate the responses of some drugs. For computer researchers, they can build distributed, robust and fault tolerant networks inspired by the functions of the immune system. This paper provides a comprehensive survey of the literatures on modelling the immune system. From the methodology perspective, the paper compares and analyzes the existing approaches and models, and also demonstrates the focusing research effort on the future immune models in the next few years.
ISSN:1672-6529
2543-2141
DOI:10.1016/S1672-6529(08)60101-8