Allergic recurrent coronary stent thrombosis: A mini-review of Kounis syndrome

Kounis syndrome (KS) consists of an association between hypersensitivity reactions triggered by various environmental and pharmacological factors and acute coronary syndromes. Blood supply may be compromised by either vasospasm (type I), native plaque destabilization (type II) or stent thrombosis (t...

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Bibliographic Details
Published in:Cardiovascular revascularization medicine 2018-10, Vol.19 (7), p.890-895
Main Authors: Ferreira, Roberto M., Villela, Paolo B., Almeida, Juliano C.G., Sampaio, Pedro Paulo N., Albuquerque, Felipe N., Pinheiro, Fernanda M.C., França Filho, William, Salles, José Ary B. e, Mansur Filho, João
Format: Article
Language:English
Subjects:
Allergy
Cardiovascular disease
Stent Thrombosis
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Summary:Kounis syndrome (KS) consists of an association between hypersensitivity reactions triggered by various environmental and pharmacological factors and acute coronary syndromes. Blood supply may be compromised by either vasospasm (type I), native plaque destabilization (type II) or stent thrombosis (type III). Although the prognosis is generally favorable, treatment should include aggressive anti-thrombotic and anti-allergic therapies. A case compatible with type III KS, manifested as a macular rash followed by two episodes of stent thrombosis after primary angioplasty (PCI) of the right coronary artery is presented, and complemented by a review on the topic.
ISSN:1553-8389
1878-0938
DOI:10.1016/j.carrev.2018.03.001