Retransplant Due to Fulminant Hepatic Failure From Hepatitis E Virus: A Case Report

Hepatitis E virus (HEV) usually causes self-limiting acute liver infections from fecal or oral transmission, though other routes of infection exist (vertical transmission, blood transfusion, zoonosis). It may give rise to fulminant hepatic failure in 1% of cases. Cases have recently been reported of...

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Bibliographic Details
Published in:Transplantation proceedings 2018-03, Vol.50 (2), p.685-686
Main Authors: Tenorio González, E., Robles Díaz, M., Sanjuan Jiménez, R., González Grande, R., Olmedo Martín, R.V., Rodrigo López, J.M., Jiménez Pérez, M.
Format: Article
Language:English
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Summary:Hepatitis E virus (HEV) usually causes self-limiting acute liver infections from fecal or oral transmission, though other routes of infection exist (vertical transmission, blood transfusion, zoonosis). It may give rise to fulminant hepatic failure in 1% of cases. Cases have recently been reported of chronic infection evolving to cirrhosis in immunosuppressed patients, such as those with a liver or kidney transplant. Nonetheless, development of acute liver failure in these patients is exceptional, with few cases published. We present a case of acute liver failure due to HEV in a liver transplant patient who required a liver retransplant 9 years after receiving the original transplant. •Acute HEV infection can occur in developed countries after consuming infected meat.•It can cause liver failure or lead to chronicity/cirrhosis, if immunosuppressed.•Acute HEV infection should be ruled out in unexplained hepatitis, even if nonendemic.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2017.09.059