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Cadmium-Induced Oxidative Stress in the Bivalve Mollusk Modiolus modiolus

Cadmium-induced oxidative stress in the bivalve Modiolus modiolus is studied from the standpoint of the universality of the mechanism of free-radical oxidation. The kinetics of cadmium accumulation by the bivalve was revealed in a laboratory experiment. The gills accumulated higher Cd levels than th...

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Bibliographic Details
Published in:Russian journal of marine biology 2005-09, Vol.31 (5), p.309-313
Main Authors: Dovzhenko, N. V., Kurilenko, A. V., Bel'cheva, N. N., Chelomin, V. P.
Format: Article
Language:English
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Summary:Cadmium-induced oxidative stress in the bivalve Modiolus modiolus is studied from the standpoint of the universality of the mechanism of free-radical oxidation. The kinetics of cadmium accumulation by the bivalve was revealed in a laboratory experiment. The gills accumulated higher Cd levels than the digestive gland. In the process of cadmium accumulation, there was an increase in lipid peroxidation products (malondialdehyde and lipofuscin) and a reduction in the total oxiradical scavenging capacity (TOSC). Cadmium induces oxidative stress in molluscan tissues through damage to the antioxidation system. Thus, TOSC can provide a useful biochemical indicator of early pathological changes in the cell or the organism, as well as of the environmental effects of heavy metal pollution.
ISSN:1063-0740
1608-3377
DOI:10.1007/s11179-005-0093-7