Association between iron‐deficiency anemia and depression: A web‐based Japanese investigation

Aim This web‐based survey aimed to examine the relation between iron‐deficiency anemia and depression in 11 876 Japanese participants. Methods Participants consisted of 1000 individuals with self‐reported history of depression (mean age, 41.4 ± 12.3 years; 499 women) and 10 876 population‐based cont...

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Bibliographic Details
Published in:Psychiatry and clinical neurosciences 2018-07, Vol.72 (7), p.513-521
Main Authors: Hidese, Shinsuke, Saito, Kenji, Asano, Shinya, Kunugi, Hiroshi
Format: Article
Language:English
Subjects:
6‐item Kessler Scale
Anemia
depression
Iron
Iron deficiency
iron‐deficiency anemia
Mental depression
Nutrient deficiency
nutritional status
sex difference
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Summary:Aim This web‐based survey aimed to examine the relation between iron‐deficiency anemia and depression in 11 876 Japanese participants. Methods Participants consisted of 1000 individuals with self‐reported history of depression (mean age, 41.4 ± 12.3 years; 499 women) and 10 876 population‐based controls (mean age, 45.1 ± 13.6 years; 5185 women). The 6‐item Kessler Scale (K6) score was used as a psychological distress scale. The design of the study was cross‐sectional. Results The rate of self‐reported lifetime history of iron‐deficiency anemia was higher in the depression group in both men (depression, 7.2%; control, 4.0%; P 
ISSN:1323-1316
1440-1819
DOI:10.1111/pcn.12656