Transdermal Patch Medication Delivery Systems and Pediatric Poisonings, 2002-2006

Transdermal drug delivery systems are an increasingly popular method of medication delivery containing large quantities of medication and presenting new opportunities for toxicity. To provide a description of exposures to transdermal medications in a pediatric population, we studied exposures in ind...

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Bibliographic Details
Published in:Clinical pediatrics 2008-09, Vol.47 (7), p.659-663
Main Authors: Parekh, Dina, Miller, Michael A., Borys, Doug, Patel, Paresh R., Levsky, Marc E.
Format: Article
Language:English
Subjects:
Administration, Cutaneous
Child
Children
Drug delivery
Exposure
Female
Humans
Male
Nonprescription Drugs - administration & dosage
Opioids
Pediatrics
Poisoning
Poisoning - diagnosis
Poisoning - epidemiology
Poisoning - etiology
Population studies
Retrospective Studies
Reviews
Texas - epidemiology
Toxicity
Transdermal medication
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Summary:Transdermal drug delivery systems are an increasingly popular method of medication delivery containing large quantities of medication and presenting new opportunities for toxicity. To provide a description of exposures to transdermal medications in a pediatric population, we studied exposures in individuals less than 12 years of age. This is a retrospective database study in which the Texas Poison Center Network database from 2002 to 2006 was reviewed. In all, 336 poison control center records of patch exposures over the 5-year period were identified. Of those, 110 cases involved children less than 12 years old. A majority of cases resulted in no significant clinical effects. One death resulted from opioid toxicity. Although a majority of patch exposures in children less than 12 years of age resulted in no significant clinical toxicity, practitioners and the public must be made aware of the available patch-based medications and their potential for toxicity in children.
ISSN:0009-9228
1938-2707
DOI:10.1177/0009922808315211