Genetic testing for young women with breast cancer

Copson and colleagues did not find a significant protective effect of bilateral mastectomy on breast cancer death after a mean follow-up of 8·2 years; however, only 21 (6·2%) women with a mutation had a bilateral mastectomy, even though, among carriers, the 10-year cumulative risk of contralateral b...

Full description

Saved in:
Bibliographic Details
Published in:The lancet oncology 2018-04, Vol.19 (4), p.e182-e182
Main Authors: Metcalfe, Kelly, Akbari, Mohammad R, Narod, Steven A
Format: Article
Language:English
Subjects:
Breast cancer
Breast Neoplasms - genetics
Female
Genetic screening
Genetic Testing
Germ Cells
Health risk assessment
Humans
Mastectomy
Mutation
Prospective Studies
Women
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Copson and colleagues did not find a significant protective effect of bilateral mastectomy on breast cancer death after a mean follow-up of 8·2 years; however, only 21 (6·2%) women with a mutation had a bilateral mastectomy, even though, among carriers, the 10-year cumulative risk of contralateral breast cancer is 30% at 5 years2 and 54 participants were reported to have contralateral breast cancer (which might have been prevented).
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(18)30162-1