De-escalation of breast radiotherapy after conserving surgery in low-risk early breast cancer patients

The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radi...

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Bibliographic Details
Published in:Medical oncology (Northwood, London, England) London, England), 2018-05, Vol.35 (5), p.62-14, Article 62
Main Authors: Franco, Pierfrancesco, Iorio, Giuseppe Carlo, Bartoncini, Sara, Airoldi, Mario, De Sanctis, Corrado, Castellano, Isabella, Ricardi, Umberto
Format: Article
Language:English
Subjects:
Breast cancer
Hematology
Internal Medicine
Mastectomy
Medicine
Medicine & Public Health
Oncology
Pathology
Radiation therapy
Review Article
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Summary:The reduction in the burden related to treatment is becoming more and more important in modern oncology. Radiation therapy is a mainstay option in the postoperative setting for early breast cancer patients after breast-conserving surgery. Nowadays, different options are available to de-escalate radiotherapy in this scenario such as the use of hypofractionated whole-breast radiation, the selective delivery of the boost dose to the lumpectomy cavity, the introduction of accelerated partial breast irradiation and the omission of treatment in appropriately selected patients with low-risk features. We herein provide a review article on this topic.
ISSN:1357-0560
1559-131X
DOI:10.1007/s12032-018-1121-8