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Markov modelling of HIV infection evolution in the HAART era

The aim was to investigate the impact of the main prognostic factors on HIV evolution. A multi-state Markov model was applied in a cohort of 2126 patients to estimate impact of these factors on patients' clinical and immunological evolutions. Clinical progression and immunological deterioration...

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Bibliographic Details
Published in:Epidemiology and infection 2009-09, Vol.137 (9), p.1272-1282
Main Authors: BINQUET, C., Le TEUFF, G., ABRAHAMOVICZ, M., MAHBOUBI, A., YAZDANPANAH, Y., REY, D., RABAUD, C., CHIROUZE, C., BERGER, J. L., FALLER, J. P., CHAVANET, P., QUANTIN, C., PIROTH, L.
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Language:English
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Summary:The aim was to investigate the impact of the main prognostic factors on HIV evolution. A multi-state Markov model was applied in a cohort of 2126 patients to estimate impact of these factors on patients' clinical and immunological evolutions. Clinical progression and immunological deterioration shared most of their prognostic factors: male gender, intravenous drug use, weight loss, low haemoglobin level (
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268808001775