Microstructured optical fiber-based luminescent biosensing: Is there any light at the end of the tunnel? - A review

This review covers the current state of the art of luminescent biosensors based on various types of microstructured optical fiber. The unique optical and structural properties of this type of optical fiber make them one of the most promising integrated platforms for bioassays. The individual section...

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Bibliographic Details
Published in:Analytica chimica acta 2018-08, Vol.1019, p.14-24
Main Authors: Pidenko, Sergey A., Burmistrova, Natalia A., Shuvalov, Andrey A., Chibrova, Anastasiya A., Skibina, Yulia S., Goryacheva, Irina Y.
Format: Article
Language:English
Subjects:
Bioassays
Biomolecules
Biosensor
Biosensors
Data processing
Fibers
Luminescence
Microstructure
Microstructured optical fibers microstructured optical waveguide
Optical fibers
Optical properties
Optical sensing
Optics
Photonic crystal fiber
Reviews
Signal processing
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Summary:This review covers the current state of the art of luminescent biosensors based on various types of microstructured optical fiber. The unique optical and structural properties of this type of optical fiber make them one of the most promising integrated platforms for bioassays. The individual sections of this review are devoted to a) classification of microstructured optical fibers, b) microstructured optical fiber materials, c) aspects of biosensing based on the biomolecules incorporated into the microstructured optical fibers, and d) development of models for prediction of the efficiency of luminescent signal processing. The authors' views on current trends and limitations of microstructured optical fibers for biosensing as well as the most promising areas and technologies for application in analytical practice are presented. [Display omitted] •The luminescence detection in microstructed optical fibers (MSWs) is reviewed.•Current trends of application MSWs for luminescence biosensing are discussed.•Potential and limitation of MSWs based biosensors are analysed.
ISSN:0003-2670
1873-4324
DOI:10.1016/j.aca.2017.12.010