Sleep disturbance and symptom burden in sarcoidosis

Sarcoidosis is a systemic inflammatory disease associated with myriad symptoms, including fatigue. It can affect physiological processes like sleep, leading to poor sleep quality and excessive daytime sleepiness. We hypothesized that sarcoidosis patients would report more severe sleep disturbance th...

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Bibliographic Details
Published in:Respiratory medicine 2018-11, Vol.144, p.S35-S40
Main Authors: Benn, Bryan S., Lehman, Zoe, Kidd, Sharon A., Miaskowski, Christine, Sunwoo, Bernie Y., Ho, Melissa, Sun, Sara, Ramstein, Joris, Gelfand, Jeffrey M., Koth, Laura L.
Format: Article
Language:English
Subjects:
Depression
Fatigue
Sarcoidosis
Sleep disturbance
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Summary:Sarcoidosis is a systemic inflammatory disease associated with myriad symptoms, including fatigue. It can affect physiological processes like sleep, leading to poor sleep quality and excessive daytime sleepiness. We hypothesized that sarcoidosis patients would report more severe sleep disturbance than healthy controls and that relationships would be found with sleep disturbance and the severity of other symptoms. We enrolled 84 sarcoidosis patients and 30 healthy controls and recorded demographic and clinical characteristics. Self-report measures were used to assess sleep disturbance, psychosocial symptoms, and quality of life at enrollment and longitudinally. Relationships between different self-report outcomes were analyzed using correlation statistics. Using the General Sleep Disturbance Scale, 54% of sarcoidosis patients reported frequent and occasional sleep disturbance compared to only 17% of healthy controls (p 
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2018.03.021