Clinical and dermoscopic characteristics of congenital melanocytic naevi

• Published in: Journal of the European Academy of Dermatology and Venereology 2018-10, Vol.32 (10), p.1674-1680
• Main Authors: Stefanaki, C., Soura, E., Stergiopoulou, A., Kontochristopoulos, G., Katsarou, A., Potouridou, I., Rigopoulos, D., Antoniou, C., Stratigos, A.
• Format: Article
• Language: English
• Subjects: Adolescent; Child; Child, Preschool; Dermoscopy; Extremities; Female; Head and Neck Neoplasms - congenital; Head and Neck Neoplasms - diagnostic imaging; Head and Neck Neoplasms - genetics; Head and Neck Neoplasms - pathology; Humans; Infant; Male; Neoplasms, Multiple Primary - congenital; Neoplasms, Multiple Primary - diagnostic imaging; Neoplasms, Multiple Primary - genetics; Neoplasms, Multiple Primary - pathology; Nevus, Pigmented - congenital; Nevus, Pigmented - diagnostic imaging; Nevus, Pigmented - genetics; Nevus, Pigmented - pathology; Skin Neoplasms - congenital; Skin Neoplasms - diagnostic imaging; Skin Neoplasms - genetics; Skin Neoplasms - pathology; Torso; Tumor Burden
• ISSN: 0926-9959; 1468-3083
• DOI: 10.1111/jdv.14988

Background Prompted by the limited data, we conducted this study to gather more information on dermoscopic features of CN in children, in order to optimize clinical care and management. Materials and methods All children with congenital nevi (CN) attending our Pediatric Pigmented Skin Lesion Unit during a 2‐year period were included in the study. Clinical data were collected, and all children underwent clinical and dermoscopic examination. Dermoscopic patterns and specific features were recorded. Results Three hundred and thirty CN were examined in a population of 276 children, aged from 6 months to 14 years. The majority (85.14%) had only one congenital naevus, and 43.12% had a family history of congenital nevi. Children with multiple congenital nevi were more likely to have a positive family history of a CN (P = 0.012). Only, in 23 children, neurological/developmental abnormalities were reported. Small CN were the commonest in our cohort (167) followed by the medium‐sized (160), whereas large CN (>20 cm) were only three. Thirty‐eight CN were located on the volar skin. The globular was the commonest dermoscopic pattern, followed by the reticular, whereas the parallel furrow pattern was the commonest pattern on palms and soles. CN on the trunk were more likely to be globular on the limbs, and reticular and homogeneous on the head and neck (P < 0.001). The commonest dermoscopic findings were haloed and target globules, blotches and perifollicular hypopigmentation, whereas globules and dots around cristae on volar skin. CN located on the limbs were more likely to demonstrate an atypical network (P = 0.001) and a target network with globules (P = 0.020), whereas haloed and target globules (P < 0.001), blotches (P = 0.023) and dots (P = 0.004) were found with an increased frequency in CN on the trunk. Conclusions Given that there is much controversy on the management and accurate classification of CN, our findings may provide useful information.