Dietary intervention and health in patients with systemic lupus erythematosus: A systematic review of the evidence

Objective: The aim of this study was to evaluate the scientific evidence of dietary intervention, either through diet or supplementation, and its effects on the health of patients with systemic lupus erythematosus. Methods: Literature searches were conducted using Scopus, PubMed, BioMed Central and...

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Bibliographic Details
Published in:Critical reviews in food science and nutrition 2019-09, Vol.59 (16), p.2666-2673
Main Authors: de Medeiros, Marília Cristina Santos, Medeiros, Jussara Cristina Alves, de Medeiros, Humberto Jefferson, Leitão, José Carlos Gomes de Carvalho, Knackfuss, Maria Irany
Format: Article
Language:English
Subjects:
Autoimmune diseases
Blood pressure
Body weight loss
Calciferol
Chronic conditions
Diet
Dietary supplements
Fatty acids
Glycemic index
Hematuria
Humans
Inflammation
intervention
Literature reviews
Lupus
Lupus Erythematosus, Systemic - diet therapy
Nutrient deficiency
Nutrition
nutrition support
Nutrition therapy
Nutritional Support
Omega-3 fatty acids
Oxidative stress
Proteinuria
Serum levels
Systemic lupus erythematosus
Vitamin D
Weight loss
Weight reduction
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Summary:Objective: The aim of this study was to evaluate the scientific evidence of dietary intervention, either through diet or supplementation, and its effects on the health of patients with systemic lupus erythematosus. Methods: Literature searches were conducted using Scopus, PubMed, BioMed Central and Science Direct databases. The terms used for the search were diet, nutritional support, nutrition therapy and systemic lupus erythematosus. Results: Eleven studies with interventions related to supplementation of omega-3 fatty acids, vitamin D and turmeric, as well as changes in diet composition, such as low glycaemic index diet were identified. Conclusions: The studies evidenced that omega-3 supplementation reduced inflammation, disease activity, endothelial dysfunction and oxidative stress; vitamin D supplementation increased serum levels, reduced inflammatory and hemostatic markers; turmeric supplementation reduced proteinuria, hematuria and systolic blood pressure; and low glycaemic index diet caused weight loss and reduced fatigue.
ISSN:1040-8398
1549-7852
DOI:10.1080/10408398.2018.1463966