Antibacterial and antioxidant activities of Origanum compactum essential oil

In the present study, essential oil of Origanum compactum was analysed and its chemical composition was identified by gas chromatography coupled to mass spectrometry (GC-MS). Among thirty two assayed constituents, carvacrol (30.53%), thymol (27.50%) and its precursor g-terpinene (18.20%) were found...

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Bibliographic Details
Published in:African journal of biotechnology 2008-05, Vol.7 (10), p.1563-1570
Main Authors: Bouhdid, S, Skali, S N, Idaomar, M, Zhiri, A, Baudoux, D, Amensour, M, Abrini, J
Format: Article
Language:English
Subjects:
Origanum
Pseudomonas
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Summary:In the present study, essential oil of Origanum compactum was analysed and its chemical composition was identified by gas chromatography coupled to mass spectrometry (GC-MS). Among thirty two assayed constituents, carvacrol (30.53%), thymol (27.50%) and its precursor g-terpinene (18.20%) were found to be the major components. The oil was investigated for its in vitro antibacterial activity against a panel of standard reference strains using well diffusion and broth dilution methods. In solid medium, the oil was found to be remarkably active against all tested strains except Pseudomonas which showed resistance. In liquid medium the Minimum Inhibitory Concentrations (MICs) and Minimum Bactericidal Concentration (MBCs) ranged from 0.0078 to 0.25% (v/v). The antioxidant activity was investigated by three different methods; 1,1-diphenyl-2-picryl-hydrasyl (DPPH) radical scavenging assay, beta -carotene bleaching test and reducing power. The results of this study revealed evidence that the essential oil of O. compactum possesses a good antioxidant effect with all assays; the antioxidant activity is dependent on the oil concentration and can be attributed to the phenolic compounds present in the oil.
ISSN:1684-5315
1684-5315