Antioxidative and antibacterial activity of the methanol extract of Artemisia anomala S. Moore

The antibacterial and antioxidative activities of the methanol extract of Artemisia anomala S. Moore were investigated. The methanol extract was subjected to screening for their possible antioxidative activities by using 2, 2'-diphenyl-1-picrylhydrazyl (DPPH) and beta -carotene bleaching method...

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Bibliographic Details
Published in:African journal of biotechnology 2008-05, Vol.7 (9), p.1335-1338
Main Authors: Guangrong, H, Jiaxin, J, Dehui, D
Format: Article
Language:English
Subjects:
Anomala
Artemisia
Escherichia
Proteus vulgaris
Salmonella typhi
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Summary:The antibacterial and antioxidative activities of the methanol extract of Artemisia anomala S. Moore were investigated. The methanol extract was subjected to screening for their possible antioxidative activities by using 2, 2'-diphenyl-1-picrylhydrazyl (DPPH) and beta -carotene bleaching methods. In the former case, the methanol extract was found to have better antioxidative activity than synthetic antioxidant butylated hydroxytoluene (BHT) with IC sub(50) value of 16.8 and 19.4 mu g/ml, respectively. The extract seemed to inhibit the oxidation of linoleic acid with an 89% inhibition in the latter case. The methanol extract from A. anomala had great antibacterial activity against all five test bacteria and most activity against Gram-negative ones. The minimum inhibitory concentration (MIC) against Proteus vulgaris, Escherichia coll and Salmonella typhi were 1.5, 4.5, 3.9 mg/ml, respectively.
ISSN:1684-5315
1684-5315