Preliminary Results of Acoustic Radiation Force Impulse Imaging by Combined Qualitative and Quantitative Analyses for Evaluation of Breast Lesions

Objectives The purpose of this study was to evaluate the application of a new elastographic technique, acoustic radiation force impulse (ARFI) imaging, and its diagnostic performance for characterizing breast lesions. Methods One hundred consecutive female patients with 126 breast lesions were enrol...

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Bibliographic Details
Published in:Journal of ultrasound in medicine 2018-10, Vol.37 (10), p.2405-2412
Main Authors: Wang, Lin, Wan, Cai‐Feng, Du, Jing, Li, Feng‐Hua
Format: Article
Language:English
Subjects:
acoustic radiation force impulse imaging
Adolescent
Adult
Aged
Aged, 80 and over
breast (diagnostic)
Breast - diagnostic imaging
breast cancer
Breast Neoplasms - diagnostic imaging
Diagnosis, Differential
Elasticity Imaging Techniques - methods
Evaluation Studies as Topic
Female
Humans
Middle Aged
qualitative analysis
quantitative analysis
Reproducibility of Results
Ultrasonography, Mammary - methods
Young Adult
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Summary:Objectives The purpose of this study was to evaluate the application of a new elastographic technique, acoustic radiation force impulse (ARFI) imaging, and its diagnostic performance for characterizing breast lesions. Methods One hundred consecutive female patients with 126 breast lesions were enrolled in our study. After routine breast ultrasound examinations, the patients underwent ARFI elasticity imaging. Virtual Touch tissue imaging (VTI) and Virtual Touch tissue quantification (Siemens Medical Solutions, Mountain View, CA) were used to qualitatively and quantitatively analyze the elasticity and hardness of tumors. A receiver operating characteristic curve analysis was performed to evaluate the diagnostic performance of ARFI for discrimination between benign and malignant breast lesions. Results Pathologic analysis revealed 40 lesions in the malignant group and 86 lesions in the benign group. Different VTI patterns were observed in benign and malignant breast lesions. Eighty lesions (93.0%) of benign group had pattern 1, 2, or 3, whereas all pattern 4b lesions (n = 20 [50.0%]) were malignant. Regarding the quantitative analysis, the mean VTI‐to‐B‐mode area ratio, internal shear wave velocity, and marginal shear wave velocity of benign lesions were statistically significantly lower than those of malignant lesions (all P 
ISSN:0278-4297
1550-9613
DOI:10.1002/jum.14599