Effect of regional cerebral oximetry to estimate neurologic prognostic outcomes in patients administered targeted temperature management

The aim of our study is to research the role and efficacy of cerebral oximetry in predicting neurologic prognosis when applied during TTM to patients experiencing coma after CA. This study was performed on surviving adult comatose patients after CA treated with TTM. The average scores of rSO2 was me...

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Bibliographic Details
Published in:The American journal of emergency medicine 2018-12, Vol.36 (12), p.2236-2241
Main Authors: Sarıtaş, Aykut, Çinleti, Burcu Acar, Zincircioğlu, Çiler, Uzun, Uğur, Köse, Işıl, Şenoğlu, Nimet
Format: Article
Language:English
Subjects:
Anesthesia
Body temperature
Cerebral oximetry
Coma
Cooling
Emergency medical care
Heart rate
Hemoglobin
Intensive care
Lactic acid
Medical prognosis
Monitoring methods
Mortality
Neurologic outcome
Oximetry
Patients
Persistent vegetative state
Prognosis
Statistical analysis
Target temperature management
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Summary:The aim of our study is to research the role and efficacy of cerebral oximetry in predicting neurologic prognosis when applied during TTM to patients experiencing coma after CA. This study was performed on surviving adult comatose patients after CA treated with TTM. The average scores of rSO2 was measured at 6h intervals for the first 2days and once a day for the following 3days with a NIRS device during TTM. The CPC scale was used to define the neurologic outcomes of patients. We compared the correlations of rSO2 values between good (CPC 1–2) and poor (CPC 3–5) neurologic outcomes in CA patients. There was no statistically significant difference identified between the prognosis groups in terms of rSO2, CPR durations, hemoglobin values and admission body temperature (p>0.05). When the variation in rSO2 values over time is investigated, though there was no significant difference between the good and poor prognosis groups, it appeared to fall in the first 6h in both prognosis groups. The median NT-proBNP and lactate values were observed to be higher in the poor prognosis group. There is no significant correlation between rSO2 values and neurologic outcomes. Multimodal monitoring methods may be useful and further studies with a larger patient population are necessary in this area.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2018.04.016