Epidemiology of pediatric nickel sensitivity: Retrospective review of North American Contact Dermatitis Group (NACDG) data 1994-2014

Nickel is a common allergen responsible for allergic contact dermatitis. To characterize nickel sensitivity in children and compare pediatric cohorts (≤5, 6-12, and 13-18 years). Retrospective, cross-sectional analysis of 1894 pediatric patients patch tested by the North American Contact Dermatitis...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2018-10, Vol.79 (4), p.664-671
Main Authors: Warshaw, Erin M., Aschenbeck, Kelly A., DeKoven, Joel G., Maibach, Howard I., Taylor, James S., Sasseville, Denis, Belsito, Donald V., Fowler, Joseph F., Zug, Kathryn A., Zirwas, Matthew J., Fransway, Anthony F., DeLeo, Vincent A., Marks, James G., Pratt, Melanie D., Mathias, Toby
Format: Article
Language:English
Subjects:
Adolescent
Age Distribution
allergic contact dermatitis
Child
Child, Preschool
children
Cross-Sectional Studies
Databases, Factual
Dermatitis, Allergic Contact - epidemiology
Dermatitis, Allergic Contact - etiology
Female
Humans
Hypersensitivity - epidemiology
Hypersensitivity - etiology
Hypersensitivity - physiopathology
Incidence
jewelry
Male
nickel
Nickel - adverse effects
Nickel - immunology
North America - epidemiology
North American Contact Dermatitis Group
Patch Tests
pediatric
Retrospective Studies
Risk Assessment
Sex Distribution
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Description
Summary:Nickel is a common allergen responsible for allergic contact dermatitis. To characterize nickel sensitivity in children and compare pediatric cohorts (≤5, 6-12, and 13-18 years). Retrospective, cross-sectional analysis of 1894 pediatric patients patch tested by the North American Contact Dermatitis Group from 1994 to 2014. We evaluated demographics, rates of reaction to nickel, strength of nickel reactions, and nickel allergy sources. The frequency of nickel sensitivity was 23.7%. Children with nickel sensitivity were significantly less likely to be male (P 
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2018.02.071