Surveillance of donated blood during the 2016 arbovirus outbreak in Brazil

Reports of arboviral transmission via blood transfusion may be a cause of concern among asymptomatic infected donors. This study evaluated the presence of arboviruses in donated blood products during the 2016 outbreak in Vitória da Conquista (Bahia‐Brazil). Serum samples (n = 676) were screened for...

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Bibliographic Details
Published in:Journal of medical virology 2018-08, Vol.90 (8), p.1406-1410
Main Authors: Sharma, Rohit, Costa Santos, Larissa, da Silva, Robson A., Gonçalves, Caroline V., de Melo Calado, Stéfano, Santos, Denisar P., de Andrade de Melo, Josana P., de Cássia Pontello Rampazzo, Rita, Requião, Luciana, Krieger, Marco A., Barral‐Netto, Manoel, de Oliveira, Camila I.
Format: Article
Language:English
Subjects:
Blood products
Blood transfusion
Disease transmission
NAT
Outbreaks
Polymerase chain reaction
RNA-directed DNA polymerase
Serotypes
Transfusion
Virology
ZIKV
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Summary:Reports of arboviral transmission via blood transfusion may be a cause of concern among asymptomatic infected donors. This study evaluated the presence of arboviruses in donated blood products during the 2016 outbreak in Vitória da Conquista (Bahia‐Brazil). Serum samples (n = 676) were screened for ZIKV, CHIKV, and the four DENV serotypes using a one‐step reverse transcriptase‐based Real‐Time Polymerase Chain Reaction (RT‐PCR). No samples tested positive for any of the targets, whereas positive controls performed as expected. The results suggest a low risk of arboviral transmission via transfusion of blood products in the endemic area studied during the 2016 outbreak.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.25193