A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Azadirachta indica L. is a multipurpose medicinal tree of family Meliaceae. It occurs in tropical and semitropical regions of the world. Different parts of this miraculous tree are used to treat pyrexia, headache, ulcer, respiratory disorders, cancer, diabetes, leprosy, malaria, dengue, chicken pox,...

Full description

Saved in:
Bibliographic Details
Published in:Phytotherapy research 2018-07, Vol.32 (7), p.1241-1272
Main Authors: Saleem, Sumaira, Muhammad, Gulzar, Hussain, Muhammad Ajaz, Bukhari, Syed Nasir Abbas
Format: Article
Language:English
Subjects:
Alkaloids
Antioxidants
Azadirachta indica
Azadirachtin
bioactives
Cancer
Carbohydrates
Complications
Dengue fever
Diabetes mellitus
Drugs
Fatty acids
Fever
Flavonoids
Fungicides
Headache
Inflammation
Leprosy
Malaria
medicinal uses
Microbicides
neem
Neuroprotection
Nimbin
Pharmaceuticals
pharmacological attributes
Pharmacology
Phytochemicals
Poultry
secondary metabolites
Skin
Steroid hormones
Steroids
Terpenes
Vector-borne diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Azadirachta indica L. is a multipurpose medicinal tree of family Meliaceae. It occurs in tropical and semitropical regions of the world. Different parts of this miraculous tree are used to treat pyrexia, headache, ulcer, respiratory disorders, cancer, diabetes, leprosy, malaria, dengue, chicken pox, and dermal complications. The tree is popular for its pharmacological attributes such as hypolipidemic, antifertility, microbicidal, antidiabetic, anti‐inflammatory, hepatoprotective, antipyretic, hypoglycemic, insecticidal, nematicidal, antiulcer, antioxidant, neuroprotective, cardioprotective, and antileishmaniasis properties. A. indica is also rich in various phytochemicals for pharmaceuticals such as alkaloids, steroids, flavonoids, terpenoids, fatty acids, and carbohydrates. The fungicidal potential of the tree is due to the presence of azadirachtin and nimbin. Herein, we have compiled a comprehensive review of phytochemical profile, pharmacological attributes, and therapeutic prospective of this multipurpose tree.
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.6076