Magnetic Resonance–Guided Focused Ultrasound Surgery for Bone Metastasis: From Pain Palliation to Biological Ablation?

Magnetic resonance-guided focused ultrasound surgery (MRgFUS), also known as high-intensity focused ultrasound, is a totally noninvasive procedure that combines two technologies: First, high-intensity focused ultrasound waves that are convened to thermal energy at a precise focal point which rises t...

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Bibliographic Details
Published in:Journal of pain and symptom management 2018-07, Vol.56 (1), p.158-162
Main Authors: Eisenberg, Elon, Shay, Lilach, Keidar, Zohar, Amit, Amnon, Militianu, Daniela
Format: Article
Language:English
Subjects:
Ablation
Bones
Cancer surgery
Cancer therapies
Cervical cancer
Consumption
Emissions
Metastasis
NMR
Nuclear magnetic resonance
Opioids
Pain
Positron emission tomography
Surgery
Tomography
Uptake
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Summary:Magnetic resonance-guided focused ultrasound surgery (MRgFUS), also known as high-intensity focused ultrasound, is a totally noninvasive procedure that combines two technologies: First, high-intensity focused ultrasound waves that are convened to thermal energy at a precise focal point which rises tissue temperature target area to approximately 65°C to 85°C resulting in irreversible thermal ablation of the tissue. Second, magnetic resonance-based three-dimensional imaging of the focal point plus real-time monitoring of the tissue temperature in the target/one. The combination of the two technologies forms a relatively safe and effective ablative procedure. Here, Eisenberg et al present a case of a woman with cervical cancer, who received MRgFUS treatment for a painful iliac bone metastasis diagnosed by high fluorodeoxyglucose uptake on a positron emission tomography-CT study. After treatment, she reported significant reduction in pain and opioid consumption.
ISSN:0885-3924
1873-6513
DOI:10.1016/j.jpainsymman.2018.04.002