Effects of ultrasound-guided botulinum toxin type-A injections with a specific approach in spastic cerebral palsy

• Published in: Acta neurologica Belgica 2018-09, Vol.118 (3), p.429-433
• Main Authors: Büyükavcı, Raikan, Büyükavcı, Mehmet Akif
• Format: Article
• Language: English
• Subjects: Adolescent; Biomedical and Life Sciences; Biomedicine; Botulinum Toxins, Type A - administration & dosage; Botulinum Toxins, Type A - therapeutic use; Cerebral Palsy - drug therapy; Child; Child, Preschool; Female; Humans; Male; Medicine/Public Health; Muscle Spasticity - physiopathology; Muscle, Skeletal - drug effects; Muscle, Skeletal - physiopathology; Neurology; Neuromuscular Agents - administration & dosage; Neuromuscular Agents - therapeutic use; Neuroradiology; Neurosciences; Original Article; Treatment Outcome; Ultrasonography
• ISSN: 0300-9009; 2240-2993
• DOI: 10.1007/s13760-018-0929-5

The aim of this study was to detect effects of ultrasound-guided botulinum toxin type-A (US-guided BoNT-A) injections prepared according to lower extremity innervation zones on spasticity and motor function in 3–16 years children with diplegic and hemiplegic spastic cerebral palsy. This study included 25 patients between 3 and 16 years of age who admitted to our clinic in 2017, were being followed in our clinic with a diagnosis of cerebral palsy, had BoNT-A injections due to lower extremity spasticity. The US-guided BoNT-A injections were administered into the spastic muscles using a specific approach according to innervation zones of muscle. Modified Ashworth Scale (MAS) and Gross Motor Functional Classification System (GMFCS) were assessed at the baseline, and 4 and 12 weeks after the BoNT-A injections. Minimum and maximum ages of the patients were 45 and 192 months, and gender distribution was 8 females and 17 males. Significant decreases in the MAS scores of the knee and ankle tones were measured 4 and 12 weeks after the BoNT-A injection when compared to the baseline scores ( p