Surveillance and genetic characterization of rotavirus strains circulating in four states of North Indian children

Acute gastroenteritis due to Rotavirus (RV) infection is a major cause of morbidity and mortality in infants and young children worldwide. In India, around 0.1 million death reported annually due to RV illness. So, to assess the disease burden continuous surveillance of the circulating genotypes is...

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Published in:Infection, genetics and evolution genetics and evolution, 2018-08, Vol.62, p.253-261
Main Authors: Islamuddin, Mohammad, Khan, Wajihul Hasan, Gupta, Shipra, Tiku, Vasundhara Razdhan, Khan, Naushad, Akdag, Ali Ilter, Chaudhary, Sanjeev, Upadhyay, Amit, Kumar, Praveen, Ghatwala, Geeta, Ray, Pratima
Format: Article
Language:English
Subjects:
Child, Preschool
Female
G12 strain
Gastroenteritis
Genetic diversity
Genotype
Humans
India - epidemiology
Infant
Male
North India
Phylogeny
Population Surveillance
Rotavirus
Rotavirus - genetics
Rotavirus Infections - epidemiology
Rotavirus Infections - virology
Seasons
Time Factors
Vaccine
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Summary:Acute gastroenteritis due to Rotavirus (RV) infection is a major cause of morbidity and mortality in infants and young children worldwide. In India, around 0.1 million death reported annually due to RV illness. So, to assess the disease burden continuous surveillance of the circulating genotypes is needed. This study aimed to ascertain the genetic variance of 429 rotavirus positive specimens observed during the period October 2013–September 2014 at four study centers from North India. Out of 1057 patients enrolled, 1018 stool samples were collected at four centers in four different states of North India. Children aged
ISSN:1567-1348
1567-7257
DOI:10.1016/j.meegid.2018.04.030