Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus)

15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration...

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Bibliographic Details
Published in:African journal of biotechnology 2007-05, Vol.6 (10), p.1236-1238
Main Authors: Kayode A, O, Olusegun R, J, Olamide A, A, Idowu O, O, Sunday J, J, Tolulope O, O
Format: Article
Language:English
Subjects:
Garcinia cambogia
Rattus
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Summary:15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration was done orally once a day, six days a week for six weeks. The routine histological preparation at the end of administration revealed increase in the interstitial spaces, degeneration of the Ledgid cells and distortion in the arrangement of the cells of spermatogenic series. The sperm counts revealed a significant increase in the experimental groups when compared statistically with the control (p
ISSN:1684-5315
1684-5315