A practical approach and algorithm for intensifying beyond basal insulin in type 2 diabetes

Despite the availability of long‐term data demonstrating the benefits of timely and aggressive intensification of antihyperglycaemic regimens among individuals with type 2 diabetes, intensification beyond basal insulin continues to be suboptimal and a global challenge. This review summarizes the evi...

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Bibliographic Details
Published in:Diabetes, obesity & metabolism obesity & metabolism, 2018-09, Vol.20 (9), p.2064-2074
Main Authors: Goldenberg, Ronald M., Assimakopoulos, Peter, Gilbert, Jeremy D., Gottesman, Irving S., Yale, Jean‐François
Format: Article
Language:English
Subjects:
Algorithms
basal insulin
Blood Glucose - drug effects
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - drug therapy
Drug Administration Schedule
glucose‐lowering agents
Glycated Hemoglobin A - drug effects
Humans
Hypoglycemic Agents - administration & dosage
Insulin
Insulin, Long-Acting - administration & dosage
intensification strategies
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Description
Summary:Despite the availability of long‐term data demonstrating the benefits of timely and aggressive intensification of antihyperglycaemic regimens among individuals with type 2 diabetes, intensification beyond basal insulin continues to be suboptimal and a global challenge. This review summarizes the evidence surrounding the various options of advancing glucose‐lowering management beyond basal insulin and provides a practical algorithm to assist in optimizing patient care and enhancing glycaemic target achievements.
ISSN:1462-8902
1463-1326
DOI:10.1111/dom.13337