Adherence to the Mediterranean Diet and the Risk of Frailty in Old People: A Systematic Review and Meta-Analysis

Background Frailty is a common geriatric syndrome in old people. It remains controversial whether Mediterranean diet could prevent old people from developing into frailty. The aim of this study is to summarize the relevant studies and assess the effectiveness of adherence to Mediterranean diet on fr...

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Bibliographic Details
Published in:The Journal of nutrition, health & aging health & aging, 2018-05, Vol.22 (5), p.613-618
Main Authors: Wang, Y., Hao, Q., Su, L., Liu, Y., Liu, S., Dong, Birong
Format: Article
Language:English
Subjects:
Aged
Aging
Cross-Sectional Studies
Diet
Diet, Mediterranean - statistics & numerical data
Evidence-based medicine
Frailty
Frailty - diet therapy
Frailty - epidemiology
Frailty - prevention & control
Geriatrics/Gerontology
Humans
Low density lipoprotein
Medicine
Medicine & Public Health
Meta-analysis
Middle Aged
Neurosciences
Nutrition
Older people
Patient compliance
Performance evaluation
Primary Care Medicine
Prospective Studies
Quality of Life Research
Risk
Systematic review
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Summary:Background Frailty is a common geriatric syndrome in old people. It remains controversial whether Mediterranean diet could prevent old people from developing into frailty. The aim of this study is to summarize the relevant studies and assess the effectiveness of adherence to Mediterranean diet on frailty in old people. Method A systematic search of MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials was conducted to identify all relevant studies up to Oct 2017. We included studies regarding the associations between adherence to Mediterranean diet and risk of frailty among elders. A meta-analysis was performed to explore the effects of Mediterranean diet on frailty. Results Six studies matched the inclusion criteria, of which five were prospective and one was cross-sectional. A total of 10,210 participants from the five prospective cohort studies were included to perform the meta-analyses. In comparison with lowest adherence to Mediterranean diet, elders with highest adherence to Mediterranean diet were significantly associated with lower risk of frailty in the future (RR= 0.56, 95% CI=0.36-0.89, p=0.015). Furthermore, the pooled estimates from four studies performed among participants in western countries (European and North American) showed that higher adherence to Mediterranean diet was associated with a 52% reduced risk of frailty (RR= 0.48, 95% CI=0.32-0.72, p
ISSN:1279-7707
1760-4788
DOI:10.1007/s12603-018-1020-x