Maximum home blood pressure readings are associated with left atrial diameter in essential hypertensives

We tested the hypothesis that the maximum value of home systolic BP (MSBP) is a marker of hypertensive target organ damage (TOD). We conducted a cross-sectional study of 220 hypertensives. The subjects performed HBP monitoring using a telemonitoring system and measured their HBP for 7 days. Mean, ma...

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Bibliographic Details
Published in:Journal of human hypertension 2018-06, Vol.32 (6), p.432-439
Main Authors: Kaihara, Toshiki, Imaizumi, Yuki, Eguchi, Kazuo, Kario, Kazuomi
Format: Article
Language:English
Subjects:
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Ankle
Blood pressure
Diagnosis
Epidemiology
Essential hypertension
Fibrillation
Health Administration
Heart
Measurement
Medicine
Medicine & Public Health
Public Health
Risk factors
Sphygmomanometer
Ventricle
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Summary:We tested the hypothesis that the maximum value of home systolic BP (MSBP) is a marker of hypertensive target organ damage (TOD). We conducted a cross-sectional study of 220 hypertensives. The subjects performed HBP monitoring using a telemonitoring system and measured their HBP for 7 days. Mean, maximum, standard deviation, and coefficient of variation of SBPs were used as independent variables. Brachial–ankle pulse wave velocity, left ventricular mass index (LVMI), mean carotid intima–media thickness, and left atrial diameter index (LADI) were used as dependent variables. Mean and maximum SBPs were significantly associated with each TOD marker. MSBP showed a significantly stronger association with LADI compared to mean SBP ( p  = 0.0012) and a significant relationship with LADI independent of LVMI ( p  = 0.024). Our findings suggest that MSBP is associated with TOD measures, similar to mean SBP. These results may indicate that MSBP could be a target of intervention for patients with atrial fibrillation.
ISSN:0950-9240
1476-5527
DOI:10.1038/s41371-018-0060-3