Bone tissue engineering: Adult stem cells in combination with electrospun nanofibrous scaffolds

Since bone tissue lesions caused by several reasons and has global outbreak without any attentions to the modernity level of the countries. In the other hands treatment of patients with this problem faced to the several limitations, in this because the future of the bone lesions treatments is relate...

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Bibliographic Details
Published in:Journal of cellular physiology 2018-10, Vol.233 (10), p.6509-6522
Main Authors: Moradi, Sadegh L., Golchin, Ali, Hajishafieeha, Zahra, Khani, Mohammad‐Mehdi, Ardeshirylajimi, Abdolreza
Format: Article
Language:English
Subjects:
Bone lesions
bone tissue engineering
Bones
fabrication
Lesions
natural biopolymers
Outbreaks
Reactors
regenerative medicine and adult stem cells
Scaffolds
Stem cells
synthetic biopolymers
Therapeutic applications
Tissue engineering
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Summary:Since bone tissue lesions caused by several reasons and has global outbreak without any attentions to the modernity level of the countries. In the other hands treatment of patients with this problem faced to the several limitations, in this because the future of the bone lesions treatments is related to the future of the bone tissue engineering. This review tries to cover the most suitable stem cells and materials from either natural or synthetic sources for bone tissue engineering. These understanding points would help researchers to further uncover the application of different adult stem cell sources in electrospinning scaffolds, promotion of nanofibrous composite construct design and adult stem cell type selection to enhance cell function and bone tissue engineering, and link laboratory investigations to clinical applications. Treatment of patients with bone lesions faced to the several limitations—Bone tissue engineering can help to developing new bio‐implants for bone lesion and fractures—This review tries to cover the most suitable stem cells and materials from either natural or synthetic sources for bone tissue engineering.
ISSN:0021-9541
1097-4652
DOI:10.1002/jcp.26606