Distribution of dimethoate in the body after a fatal organphosphateintoxication

Abstract Many organophosphate pesticides (OPs) such as dimethoate are used to eradicate household pests, and those occurring in agriculture and forestry sectors. Combinations of two or more different insecticides have been manufactured to increase their effectiveness. A case of death is presented as...

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Bibliographic Details
Published in:Forensic science international 2007-08, Vol.170 (2), p.129-132
Main Authors: Tarbah, F.A, Shaheen, A.M, Benomran, F.A, Hassan, A.I, Daldrup, Th
Format: Article
Language:English
Subjects:
Aqueous solutions
Biological and medical sciences
Chlorpyrifos
Dialkyl phosphate
Dimethoate
Forensic medicine
Forensic sciences
GC/MS
General aspects
Investigative techniques, diagnostic techniques (general aspects)
Legal medicine
Medical sciences
Musculoskeletal system
Nitrogen
Pathology
Pest control
Phosphates
Post-mortem materials
Public health. Hygiene
Public health. Hygiene-occupational medicine
Suicidal poisoning
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Summary:Abstract Many organophosphate pesticides (OPs) such as dimethoate are used to eradicate household pests, and those occurring in agriculture and forestry sectors. Combinations of two or more different insecticides have been manufactured to increase their effectiveness. A case of death is presented as suspected organophosphates intoxication. Autopsy was unremarkable except for grayish fluid in the stomach, with garlicky odor. A systematic toxicological analysis on post-mortem specimens revealed high concentrations of dimethoate in blood 38 μg/mL, urine 0.47 μg/mL, brain 2.2 μg/g, myocardial muscle 7.6 μg/g, liver 4.6 μg/g, lung 7.6 μg/g, skeletal muscle 21 μg/g, kidney 55 μg/g and gall bladder 31 μg/g. Blood alcohol was 2.85 g/L, cyclohexanone and cyclohexanol were also detected in the blood but not quantified. The cause of death was determined as organophosphate intoxication.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2007.04.232