Coronary artery ectasia, an independent predictor of no-reflow after primary PCI for ST-elevation myocardial infarction

The no-reflow phenomenon is a serious complication after primary percutaneous coronary intervention (PCI) for ST-elevation Myocardial Infarction (STEMI). Coronary artery ectasia (CAE) may increase the risk of no-reflow, however, only limited data is available on the potential impact of CAE. The aim...

Full description

Saved in:
Bibliographic Details
Published in:International journal of cardiology 2018-08, Vol.265, p.12-17
Main Authors: Schram, H.C.F., Hemradj, V.V., Hermanides, R.S., Kedhi, E., Ottervanger, J.P.
Format: Article
Language:English
Subjects:
Aged
CAE
Case-Control Studies
Cohort Studies
Coronary Vessels - diagnostic imaging
Dilatation, Pathologic - diagnostic imaging
Dilatation, Pathologic - etiology
Female
Humans
Male
Middle Aged
No-reflow
No-Reflow Phenomenon - diagnostic imaging
No-Reflow Phenomenon - etiology
Percutaneous Coronary Intervention - adverse effects
Percutaneous Coronary Intervention - trends
Predictive Value of Tests
Primary percutaneous coronary intervention
Prospective Studies
Retrospective Studies
ST Elevation Myocardial Infarction - diagnostic imaging
ST Elevation Myocardial Infarction - surgery
ST-segment elevation myocardial infarction
Thrombus burden
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The no-reflow phenomenon is a serious complication after primary percutaneous coronary intervention (PCI) for ST-elevation Myocardial Infarction (STEMI). Coronary artery ectasia (CAE) may increase the risk of no-reflow, however, only limited data is available on the potential impact of CAE. The aim of this study was to determine the potential association between CAE and no-reflow after primary PCI. A case control study was performed based on a prospective cohort of STEMI patients from January 2000 to December 2011. All patients with TIMI 0–1 flow post primary PCI, in the absence of dissection, thrombus, spasm or high-grade residual stenosis, were considered as no-reflow case. Control subjects were two consecutive STEMI patients after each case, with TIMI flow ≥2 after primary PCI. CAE was defined as dilatation of an arterial segment to a diameter at least 1.5 times that of the adjacent normal coronary artery. In the no-reflow group, frequency of CAE was significantly higher (33.8% vs 3.9%, p 
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2018.04.120