Role of mean platelet volume and neutrophil/lymphocyte ratio to predict single-dose methotrexate treatment success in tubal ectopic pregnancy

The aim of the study was to evaluate the value of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) to predict single-dose methotrexate (MTX) treatment success in ectopic pregnancy (EP). A total of 115 EP diagnosed and hemodynamically stable women were enrolled in the study and divide...

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Bibliographic Details
Published in:Clinical and experimental obstetrics & gynecology 2016-01, Vol.43 (4), p.509-511
Main Authors: Cekmez, Y, Göçmen, A, Sanlιkan, F, Türkmen, S B
Format: Article
Language:English
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Summary:The aim of the study was to evaluate the value of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) to predict single-dose methotrexate (MTX) treatment success in ectopic pregnancy (EP). A total of 115 EP diagnosed and hemodynamically stable women were enrolled in the study and divided into two groups as group 1, the treatment success group (n= 78) and group 2, the treatment failure group (n = 37). The authors compared the groups in terms of MPV and NLR. MPV and NLR levels were higher in MTX treatment successful group than in failure group.The cut-off values of MPV and NLR were determined as 10.1 fL and 1.82, respectively. These cut off values showed similar sensitivity and specificity in prediction of MTX treat- ment success. MPV and NLR can be used as reliable markers to predict single-dose MTX treatment success however further studies are needed.
ISSN:0390-6663
DOI:10.12891/ceog2152.2016