Escherichia coli isolates from patients with inflammatory bowel disease: ExPEC virulence- and colicin-determinants are more frequent compared to healthy controls

A set of 178 Escherichia coli isolates taken from patients with inflammatory bowel disease (IBD) was analyzed for bacteriocin production and tested for the prevalence of 30 bacteriocin and 22 virulence factor determinants. Additionally, E. coli phylogenetic groups were also determined. Pulsed-field...

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Bibliographic Details
Published in:International journal of medical microbiology 2018-07, Vol.308 (5), p.498-504
Main Authors: Micenková, Lenka, Frankovičová, Lucia, Jaborníková, Iva, Bosák, Juraj, Dítě, Petr, Šmarda, Jan, Vrba, Martin, Ševčíková, Alena, Kmeťová, Marta, Šmajs, David
Format: Article
Language:English
Subjects:
Bacteriocin
Crohn’s disease
E. coli
Phylogenetic group
Ulcerative colitis
Virulence
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Summary:A set of 178 Escherichia coli isolates taken from patients with inflammatory bowel disease (IBD) was analyzed for bacteriocin production and tested for the prevalence of 30 bacteriocin and 22 virulence factor determinants. Additionally, E. coli phylogenetic groups were also determined. Pulsed-field gel electrophoresis (PFGE) was used for exclusion of clonal character of isolates. Results were compared to data from a previously published analysis of 1283 fecal commensal E. coli isolates. The frequency of bacteriocinogenic isolates (66.9%) was significantly higher in IBD E. coli compared to fecal commensal E. coli isolates (54.2%, p 
ISSN:1438-4221
1618-0607
DOI:10.1016/j.ijmm.2018.04.008