Magnesium Sulfate Reduced Opioid Consumption in Obese Patients Undergoing Sleeve Gastrectomy: a Prospective, Randomized Clinical Trial

Objective The purpose of the study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation. Design A prospective, randomized, placebo-controlled clinical study. Setting University hospital. Participants Eighty patients undergoing sleeve gastr...

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Bibliographic Details
Published in:Obesity surgery 2018-09, Vol.28 (9), p.2783-2788
Main Authors: Kizilcik, Nurcan, Koner, Ozge
Format: Article
Language:English
Subjects:
Anesthesia
Clinical trials
Gastrointestinal surgery
Medicine
Medicine & Public Health
Narcotics
Obesity
Original Contributions
Pain
Pain management
Patients
Surgery
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Summary:Objective The purpose of the study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation. Design A prospective, randomized, placebo-controlled clinical study. Setting University hospital. Participants Eighty patients undergoing sleeve gastrectomy. Measurements and Main Results Visual analog scale for the evaluation of pain, sedation score, mean arterial pressure, heart rate, and total analgesic consumption was recorded. Serum magnesium levels were determined before the operation, at the end of the operation, and at 24 h. There were no significant differences between the groups with respect to demographics, and sedation scores. Cumulative morphine consumption and pain scores were found to be higher in the control group than the magnesium group. Conclusion Perioperative use of magnesium sulfate reduced postoperative pain and opioid consumption in obese patients undergoing sleeve gastrectomy operations.
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-018-3243-7