HPLC and NMR analysis of the phenyl-ethanoid glycosides pattern of Verbascum thapsus L. cultivated in the Etnean area

In this work the HPLC and NMR analysis of the phenyl-ethanoid glycosides (PhGs) pattern of a cultivated exemplar of Verbascum thapsus L. (Scrophulariaceae) from the Etnean area (Sicily, Italy) was performed in order to verify their possible presence. Wild V. thapsus is well-known in ethnopharmacolog...

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Bibliographic Details
Published in:Natural product research 2019-05, Vol.33 (9), p.1310-1316
Main Authors: Frezza, Claudio, Bianco, Armandodoriano, Serafini, Mauro, Foddai, Sebastiano, Salustri, Manuel, Reverberi, Massimo, Gelardi, Luca, Bonina, Andrea, Bonina, Francesco Paolo
Format: Article
Language:English
Subjects:
chemotaxonomy
cultivated plant
Ethnopharmacology
Glycosides
High-performance liquid chromatography
HPLC
Liquid chromatography
Natural products
NMR
Nuclear magnetic resonance
Pharmacology
phenyl-ethanoid glycosides
Verbascum thapsus
Verbascum thapsus L
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Summary:In this work the HPLC and NMR analysis of the phenyl-ethanoid glycosides (PhGs) pattern of a cultivated exemplar of Verbascum thapsus L. (Scrophulariaceae) from the Etnean area (Sicily, Italy) was performed in order to verify their possible presence. Wild V. thapsus is well-known in ethnopharmacology due to the several beneficial effects that it is able to exert and which are primarily due to these compounds. So, it's extremely important that also cultivated exemplars of this species biosynthesize them in order to maintain their pharmacological properties. This study revealed the presence of seven PhGs in an unusual novel pattern. Thus, this exemplar is a very good potential source of this class of natural products and may be employed for several beneficial ethnopharmacological purposes.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2018.1473398