A novel electrochemical sensor for detecting hyperin with a nanocomposite of ZrO2-SDS-SWCNTs as decoration

• Published in: Talanta (Oxford) 2018-08, Vol.185, p.453-460
• Main Authors: Li, Shuo, Lei, Sheng, Yu, Qian, Zou, Lina, Ye, Baoxian
• Format: Article
• Language: English
• Subjects: Hyperin; Modified material; SWCNTs; Voltammetric sensor; ZrO2
• ISSN: 0039-9140; 1873-3573
• DOI: 10.1016/j.talanta.2018.04.008

A novel high-sensitive electrochemical sensor with glassy carbon electrode (GCE) as support for hyperin determination is successfully designed and constructed, and the well-shaped nano-meter modified material is synthesized via a one-step and facile route. Functionalized with surfactant sodium dodecyl sulfate (SDS), Single-Walled Carbon Nanotubes (SWCNTs) are synchronously grafted with ZrO2 nanoparticles to develop into the as-prepared nano-composite (ZrO2-SDS-SWCNTs). Compared to the previous reports related with hyperin detection, the linear range gets wider and detection limit (LOD) becomes lower with the aid of this novel nano-composite modified glassy carbon electrode (ZrO2-SDS-SWCNTs/GCE). The crystalline phases and functionalization of the preparation process has been investigated by X-ray diffraction (XRD) and Fourier transform infrared (FT-IR) instrument analysis, respectively, and the micro-morphology of related modified materials is also visibly characterized by scanning electron microscope (SEM) and transmission electron microscope (TEM). In addition, electrochemical properties of the modified materials are comparably explored by means of impedance spectroscopy (EIS) and cyclic voltammograms (CV). According to the established calibration curve under optimized condition, the peak current (Differential pulse voltammetry (DPV) signal) keeps a linear relationship with hyperin concentration in the ranges of 1.0 × 10−9 − 3.0 × 10−7 mol L−1, meanwhile detection limit reaches as low as 5 × 10−10 mol L−1 (S/N = 3). As for practical applications, the proposed sensor has also worked well on sensitive hyperin determination in real species Abelmoschus manihot. [Display omitted] •A highly sensitive sensor ZrO2-SDS-SWCNTs/GCE was fabricated for the first time.•This work offered a wider linear range and a lower detection limit for hyperin assay.•The as-designed sensor demonstrated feasibility in real sample Abelmoschus manihot.