Simultaneous presence of C-ANCA and P-ANCA in a patient with concurrent Churg-Strauss syndrome and giant cell temporal arteritis: CASE REPORT

We herein describe the case of a 77-year-old woman, who presented clinical and histopathological evidence of giant cell arteritis (GCA) involving the temporal artery, together with a Churg-Strauss syndrome (CSS). Our patient presented positive anti­neutrophil cytoplasmic antibodies (ANCA), with cyto...

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Bibliographic Details
Published in:Scandinavian journal of rheumatology 2000-01, Vol.29 (1), p.68-69
Main Author: J.M. Guardiola, A. Rodríguez-Pla, J. López-Contreras, J.M. Llobet, P. Domingo, M. Franco, C. Díaz, G. Vázquez
Format: Article
Language:English
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Summary:We herein describe the case of a 77-year-old woman, who presented clinical and histopathological evidence of giant cell arteritis (GCA) involving the temporal artery, together with a Churg-Strauss syndrome (CSS). Our patient presented positive anti­neutrophil cytoplasmic antibodies (ANCA), with cytoplasmic staining pattern (C-ANCA) that was specific against proteinase 3 (PR3), and also a perinuclear pattern (P-ANCA) with specificity against myeloperoxidase (MPO). To our knowledge, the simultaneous presence in the same patient of both types of antibodies has not been previously reported.
ISSN:0300-9742
1502-7732
DOI:10.1080/030097400750001842