An initial study on the effect of functional electrical stimulation in erectile dysfunction: a randomized controlled trial

Erectile dysfunction (ED) affects approximately 150 million men worldwide. Functional electrical stimulation (FES) therapy has shown a high regenerative capacity for smooth muscle cells and, therefore, is being increasingly adopted. FES can be a beneficial treatment option when the cause of ED is re...

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Bibliographic Details
Published in:International journal of impotence research 2018-06, Vol.30 (3), p.97-101
Main Authors: Carboni, Cristiane, Fornari, Alexandre, Bragante, Karoline C., Averbeck, Marcio A., Vianna da Rosa, Patrícia, Mea Plentz, Rodrigo Della
Format: Article
Language:English
Subjects:
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Analysis
Care and treatment
Clinical trials
Electric stimulation
Erectile dysfunction
Evidence-based medicine
Impotence
Males
Medicine
Medicine & Public Health
Quality of life
Reproductive Medicine
rology
Smooth muscle
Urology
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Summary:Erectile dysfunction (ED) affects approximately 150 million men worldwide. Functional electrical stimulation (FES) therapy has shown a high regenerative capacity for smooth muscle cells and, therefore, is being increasingly adopted. FES can be a beneficial treatment option when the cause of ED is related to degeneration of cavernous smooth muscle. To evaluate the impact of FES on erectile function in men with erectile dysfunction. Twenty-two patients with ED participated in this randomized clinical trial. Participants were randomly assigned to two groups: intervention (IG) or control (CG). IG participants underwent FES therapy (50 Hz/500 µs) for a total of 4 weeks, divided into two weekly sessions lasting 15 min each, with intensity lower than the motor threshold. CG participants were treated with placebo FES and followed the same routine as the IG. Erectile function was assessed by the validated International Index of Erectile Function (IIEF-5) and Erection Hardness Score (EHS), applied before and after treatment, and quality of life, by the WHOQOL questionnaire. Statistically significant differences in IIEF-5 and EHS were found between the IG and CG after treatment ( p  
ISSN:0955-9930
1476-5489
DOI:10.1038/s41443-018-0024-8