Acute pancreatitis secondary to oral contraceptive-induced hypertriglyceridemia: a case report

• Published in: Gynecological endocrinology 2018-11, Vol.34 (11), p.930-932
• Main Authors: Stumpf, Matheo Augusto Morandi, Kluthcovsky, Ana Claudia Garabeli Cavalli, Okamoto, Jefferson Matsuiti, Schrut, Gianna Carla Alberti, Cajoeiro, Patricia de Oliveira, Chacra, Ana Paula Marte, Bizeli, Ricardo
• Format: Article
• Language: English
• Subjects: Adult; Contraceptives, Oral, Synthetic - adverse effects; Estrogens - adverse effects; Ethinyl Estradiol - adverse effects; Humans; Hypertriglyceridemia - chemically induced; Hypertriglyceridemia - complications; Norpregnenes - adverse effects; Pancreatitis - etiology
• ISSN: 0951-3590; 1473-0766
• DOI: 10.1080/09513590.2018.1473365

Hypertriglyceridemia is the third most common cause of acute pancreatitis. Among the causes that lead to secondary hypertriglyceridemia, the use of contraceptive agents is the main reason to be assessed in young women. We report a case of a 31-year-old woman who had suffered two acute pancreatitis episodes secondary to hypertriglyceridemia. In the investigation, the previous medical team indicated a genetic screening before ruling out all secondary causes. LPL, apo CII and apo AV genes were negative for mutations. In the first appointment with us, the patient reported the use of a contraceptive agent for about 2 years. She was instructed to discontinue the drug. After one year of follow-up, her serum triglycerides are within the normal range and a copper intrauterine device was the method chosen by the patient for contraception.