Prosthetic Joint Infections: an Update

Purpose of Review Prosthetic joint infection (PJI) is a rare but serious complication that is frequently misdiagnosed. We aimed to highlight the nuances of PJI diagnosis and antimicrobial therapies and provide clarity in key areas of management. Recent Findings Current research in PJI centers on a p...

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Bibliographic Details
Published in:Current infectious disease reports 2018-07, Vol.20 (7), p.15-15, Article 15
Main Authors: Abad, C. L., Haleem, A.
Format: Article
Language:English
Subjects:
Biomarkers
Bone and Joint Infectious Disease
Bone and Joint Infectious Disease (N Safdar and A Pop-Vicas
Infectious Diseases
Medicine
Medicine & Public Health
Prophylaxis
Prostheses
Section Editors
Skin
Soft Tissue
Topical Collection on Skin
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Summary:Purpose of Review Prosthetic joint infection (PJI) is a rare but serious complication that is frequently misdiagnosed. We aimed to highlight the nuances of PJI diagnosis and antimicrobial therapies and provide clarity in key areas of management. Recent Findings Current research in PJI centers on a potential role for diagnostic biomarkers, molecular techniques, and implant sonication to reduce culture-negativity rates. The optimal duration of antimicrobial therapy remains controversial. Summary A high clinical index of suspicion for PJI combined with data from multiple preoperative and intraoperative tests enables timely diagnosis and treatment. Biomarkers, molecular methods, and implant sonication are currently adjunctive to traditional diagnostic techniques. Shorter courses of antimicrobial therapies as well as the role of chronic suppressive therapy need confirmation by randomized controlled trials. Existing practices for preoperative dental prophylaxis and treatment of asymptomatic bacteriuria warrant revision based on evidence arguing against risk for PJI.
ISSN:1523-3847
1534-3146
DOI:10.1007/s11908-018-0622-0