Osseointegration of Osseotite registered and machined-surfaced titanium implants in membrane-covered critical-sized defects: a histologic and histometric study in dogs

• Published in: Clinical oral implants research 2007-04, Vol.18 (2), p.153-160
• Main Authors: Veis, Alexander A, Papadimitriou, Serafim, Trisi, Paolo, Tsirlis, Anastasios T, Parissis, Nikolaos A, Kenealy, James N
• Format: Article
• Language: English
• ISSN: 0905-7161; 1600-0501
• DOI: 10.1111/j.1600-0501.2006.01316.x

The texture of an implant's surface can influence the rate and extent of bone fixation as expressed by the amount of linear bone-to-implant contact (BIC). The purpose of this study was to compare the bone density and linear BIC between Osseotite registered and machined-surface implants placed in bony defects without graft material and covered by a membrane. Thirty 2mm diameter, 10mm length custom implants were prepared for this study having a 'split surface,' with one side having the acid-etched surface and the opposite side having a machined surface. Defects were created in the iliac wing of three adult mongrel dogs where a 6-mm-diameter drill was used to generate a 5-mm-deep defect. The implants were inserted into the center of the defect with 5mm secured into the bone leaving 5mm free in the defect with a 2mm gap between the implant and surrounding bone. Expanded polytetrafluroethelyene membranes were placed over the defect sites stabilized with Biotack registered pins. The healing times were 2, 3, and 5 months. Histologic and histometric analysis showed significantly lower BIC in the defect region as compared with the portion of implant placed into native bone for both implant surfaces in all groups. There was no difference in BIC values at 2- and 5-month periods between the two surfaces in the regenerated area, while BIC values for Osseotite registered surfaces were significantly higher than the machined surfaces at 3 months' healing time. Changes in bone density, observed between the three groups, affected correspondingly the BIC values in both implant surfaces, the effect being more pronounced in the Osseotite registered surface.To cite this article: Veis AA, Papadimitriou S, Trisi P, Tsirlis AT, Parissis NA, Kenealy JN. Osseointegration of Osseotite registered and machined-surfaced titanium implants in membrane-covered critical-sized defects: a histologic and histometric study in dogs. Clin. Oral Impl. Res. 18, 2007; 153-160 doi: 10.1111/j.1600-0501.2006.01316.x