Economic burden of seasonal influenza in the United States

Seasonal influenza is responsible for a large disease and economic burden. Despite the expanding recommendation of influenza vaccination, influenza has continued to be a major public health concern in the United States (U.S.). To evaluate influenza prevention strategies it is important that policy m...

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Bibliographic Details
Published in:Vaccine 2018-06, Vol.36 (27), p.3960-3966
Main Authors: Putri, Wayan C.W.S., Muscatello, David J., Stockwell, Melissa S., Newall, Anthony T.
Format: Article
Language:English
Subjects:
Absenteeism
Age
Age groups
Cost-of-illness
Disease burden
Economic burden
Economic conditions
Economics
Emergency medical services
Estimates
Health care
Health care expenditures
Hospitalization
Illnesses
Immunization
Infections
Influenza
Laboratories
Population
Productivity
Public health
Sensitivity analysis
Time series
Vaccination
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Summary:Seasonal influenza is responsible for a large disease and economic burden. Despite the expanding recommendation of influenza vaccination, influenza has continued to be a major public health concern in the United States (U.S.). To evaluate influenza prevention strategies it is important that policy makers have current estimates of the economic burden of influenza. To provide an updated estimate of the average annual economic burden of seasonal influenza in the U.S. population in the presence of vaccination efforts. We evaluated estimates of age-specific influenza-attributable outcomes (ill-non medically attended, office-based outpatient visit, emergency department visits, hospitalizations and death) and associated productivity loss. Health outcome rates were applied to the 2015 U.S. population and multiplied by the relevant estimated unit costs for each outcome. We evaluated both direct healthcare costs and indirect costs (absenteeism from paid employment) reporting results from both a healthcare system and societal perspective. Results were presented in five age groups (
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2018.05.057