Prevalence and dynamics of Lactobacillus sp. in the lower respiratory tract of patients with cystic fibrosis

No prevalence or dynamics analysis of Lactobacilli in the lung of cystic fibrosis (CF) patients has yet been conducted. In order to use them as probiotics in the treatment of Pseudomonas aeruginosa infection, we describe their lung epidemiology. Over a period of 8 months, we analyzed 279 sputum samp...

Full description

Saved in:
Bibliographic Details
Published in:Research in microbiology 2018-05, Vol.169 (4-5), p.222-226
Main Authors: Fangous, Marie-Sarah, Lazzouni, Ismaïl, Alexandre, Youenn, Gouriou, Stéphanie, Boisramé, Sylvie, Vallet, Sophie, Le Bihan, Jean, Ramel, Sophie, Héry-Arnaud, Geneviève, Le Berre, Rozenn
Format: Article
Language:English
Subjects:
Cystic fibrosis
Lactobacillus
Probiotics
Pseudomonas aeruginosa
Respiratory tract
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:No prevalence or dynamics analysis of Lactobacilli in the lung of cystic fibrosis (CF) patients has yet been conducted. In order to use them as probiotics in the treatment of Pseudomonas aeruginosa infection, we describe their lung epidemiology. Over a period of 8 months, we analyzed 279 sputum samples from 124 CF patients classified according to their P. aeruginosa Leeds status of colonization. A total of 137 strains belonging to 11 species were isolated. The prevalence of carriage was 61%. No difference in species diversity or frequency was observed according to Leeds criteria. The next step will be to focus on the strain level.
ISSN:0923-2508
1769-7123
DOI:10.1016/j.resmic.2018.03.005